Clinically Studied
Bioidentical free-acid D-BHB has been evaluated in a highly regarded peer-reviewed clinical trial for safety and tolerability. Safe and well tolerated with no acid-base or electrolyte abnormalities.
Experience the same energy your body makes naturally...

100% bioidentical D-BHB, zero synthetic precursors
Feel the difference in minutes, no crash
Natural flavors, stevia only. No artificial ingredients
Used by leading ketogenic researchers
Original Ketone® is the ONLY pure clinically validated bioidentical D-BHB on the market. Blends are NOT bioidentical!
Your body naturally produces D-BHB when you fast or enter ketosis. Original Ketone® is biologically identical to that molecule your body recognizes on contact: nothing synthetic, nothing to process or convert.
Bioidentical free-acid D-BHB has been evaluated in a highly regarded peer-reviewed clinical trial for safety and tolerability. Safe and well tolerated with no acid-base or electrolyte abnormalities.
Unlike ketone salts, esters or blends, Original Ketone® contains no chemical byproducts or precursors. No 1,3-butanediol. No salt residue. No unknown molecules created during processing, just pure bioidentical ketone power.
Our ketone is the finished bioidentical molecule and requires zero stomach or liver processing. It's immediately bioavailable, so your brain and body use it within minutes!
D-BHB, natural flavors, and stevia. That's it. Zero artificial sweeteners, zero additives, zero mystery ingredients. Designed by Nature means everything you want and no synthetic 'frankenmolecules.' Ketone 'blends' are NOT bioidentical, your body does NOT make 1,3 butanediol alone or as a blend!
It matters because your liver matters. Most ketone supplements are chemically synthetic precursors your body still has to break down before it can use the ketone. 100% bioidentical Original Ketone® doesn't require that step, delivering the pure all natural ketone your body recognizes as energy the moment it's absorbed.
Original Ketone® is simple: just mix, drink, and feel the difference!
Best for: Pre-workout, morning clarity, afternoon slump
Mix: 2 oz Original Ketone® + 14 oz water
Serving: 10g D-BHB
Duration: 3–4 hours
Per Bottle: 8 drinks
Best for: Extended fasting, intermittent fasting, calm focus
Mix: 1 oz Original Ketone® + 15 oz water
Serving: 5g D-BHB
Drink: Between Meals
Per Bottle: 16 drinks
Start your day with a 10g boost. Feel clarity and energy without coffee jitters. Mix 2 oz concentrate with 14 oz cold water.
10g protocol delivers immediate fuel for strength or endurance training. Mix 2 oz concentrate with 14 oz cold water.
5g drink combats the 3 PM energy crash without affecting sleep. Mix 1 oz concentrate with 15 oz cold water.
5g protocol supports appetite control while maintaining fasted state. Mix 1 oz concentrate with 15 oz cold water.
"I have purchased the Original Ketone concentrate a few times now and it has been very effective in raising my ketones levels for several hours after drinking the mixture. The taste I found sweet but also refreshing as I have been on a sugar free diet for 5yrs now so it's nice to have something that tastes so good. The customer service has been fantastic. I would definitely recommend this product as it is pure with no added sugar or nasties so to me is worth it and so far the best on the market from the research I have done."
Steph B.
Goal: Metabolic Health and Wellness
"I just received my first order of Original Ketone. I'm in my early 70s and have tried many products (mostly natural) over the years to increase my flagging energy level; Original Ketone is the best and it's not close. My overall energy level is improved, mental acuity and athletic performance — extraordinarily helpful."
Jeff B.
Healthy ageing aficionado
"I never want to be out of Original Ketone. I've tried other exogenous ketones and Original Ketone is what I use daily. My focus is increased (almost immediately — I can feel it!) and my energy feels renewed, without caffeine side effects. It's easy to sip on and I can add it to just plain water. Prioritizing protein intake while staying in ketosis has been a constant struggle; Original Ketone has been the answer. Highly recommend!"
Christine D.
Focus increase fan
"I recently graduated and, while preparing for an important graduation related test and navigating several other big changes, I felt pretty overwhelmed. I started using Original Ketone as part of my routine and personally felt more clear headed and steady during my study sessions. It has become a helpful new part of my routine when I want to feel mentally prepared."
Anna B.
Clear headed under pressure
Original Ketone Concentrate
16 oz bottle / 80g pure D-BHB
Mixing Bottle (Starter Pack Only)
Pre-measured label marking for easy mixing
Quick Start Guide
Protocols, timing, storage instructions
Everything is included in our Starter Pack. You don't need to buy mixing bottles, measuring tools, or anything else. Just add water. For even greater value try our Double Value Pack!
| Protocol | Drinks | Cost/Drink | Timeline |
|---|---|---|---|
| 10g (Quick Energy Boost) | 8 | $13.50 | 8 days |
| 5g (All-Day Hunger Quieting) | 16 | $6.75 | 16 days |
| Mixed Usage | ≈12 | $9 | 12 days |
Unopened: 2 years in cool storage
Opened: 6 months if sealed tightly and refrigerated
Mixed Drink: Fresh for days or longer if refrigerated
Designed by Nature
At Original Ketone, we believe true performance comes from harmony with nature — not from lab-made shortcuts. Our bioidentical ketones are molecularly identical to the ketones your own body produces, delivering clean, efficient energy that feels natural because it is natural.
Unlike synthetic ketone salts, esters, or 1,3-butanediol concoctions, our bioidentical formula works with your metabolism, not against it. No harsh taste, no gut discomfort, no chemical overload. Just smooth, sustained mental and physical energy powered by pure ketones as nature intended.
Experience the difference nature designed. Fuel your brain and body the way evolution perfected — with Original Ketone.
Built in a lab, not by nature.
Unlock the truth about what 'bioidentical' really means for your body.
Bioidentical compounds are identical in molecular structure to substances naturally produced by the human body. This supports optimal recognition and utilization. Original Ketone is 100% bioidentical.
The body naturally produces beta-hydroxybutyrate (BHB), primarily the D-BHB isomer, but not ketone salts or 1,3 Butanediol. Ketone salts are synthesized by binding BHB to minerals and 1,3 Butanediol is a synthetic precursor.
Bioidentical = Natural Body Recognition
Ketone Salts & 1,3 Butanediol = Synthesized Compounds
| Ingredient | Does Your Body Make It? | Bioidentical? | Usable as it is? |
|---|---|---|---|
| Original Ketone D-BHB | Yes! Main ketone body made in the liver during ketosis. | Yes! Same D-isomer your body naturally produces. | Yes! Enters blood as usable ketone fuel as soon as absorbed. |
| D,L Ketone Salts | No! Body makes only D-BHB; L-BHB is not meaningfully produced. | No! Mixture of bioidentical D-BHB plus non-native L-BHB. | No! Ketone salts must be digested in the stomach before use and L-BHB is used slowly or inefficiently. |
| 1,3-Butanediol | No! Synthetic alcohol precursor converted to BHB in the liver. | No! Not produced by the body; only its metabolite (D-BHB) is bioidentical. | No! Must first be metabolized by the liver into BHB before it can act as ketone fuel. |